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SORD antibody [AT10F4]

Anti-SORD antibody [AT10F4] used in Western Blot (WB). GTX57595
Anti-SORD antibody [AT10F4] used in Western Blot (WB). GTX57595
Anti-SORD antibody [AT10F4] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX57595

Cat. No. GTX57595

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 AT10F4

Isotype

 IgG1

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μl ($399)
See all SORD products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Recommended starting dilution is 1:1000.
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 10% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The clone AT10F4 is derived from hybridization of mouse F2 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SORD protein.

Purification

Protein A Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sorbitol dehydrogenase , HELS95n , SORD , SORD1 , Sorbitol Dehydrogenase

Cellular Localization

Mitochondrion membrane,Cell projection,Cilium,Flagellum

Background

Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]

Database

Research Area

DATA IMAGES

Anti-SORD antibody [AT10F4] used in Western Blot (WB). GTX57595

GTX57595 WB Image

WB analysis of Jurkat whole cell lysate using GTX57595 SORD antibody.
Loading : 40 μg
Dilution : 1:1000

Anti-SORD antibody [AT10F4] used in Western Blot (WB). GTX57595

GTX57595 WB Image

WB analysis of various samples using GTX57595 SORD antibody.
Lane 1 : Recombinant Human SORD protein (20 ng)
Lane 2 : HeLa whole cell lysate (40 μg)

Anti-SORD antibody [AT10F4] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX57595

GTX57595 ICC/IF Image

ICC/IF analysis of Hep3B cells using GTX57595 SORD antibody.
Blue: DAPI
Green: Primary antibody
Dilution: 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399