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SOS1 antibody

Anti-SOS1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64852
Anti-SOS1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64852
Anti-SOS1 antibody used in Western Blot (WB). GTX64852

Cat. No. GTX64852

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all SOS1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

152 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1034-1333 of human SOS1 (NP_005624.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SOS Ras/Rac guanine nucleotide exchange factor 1 , GF1 , GGF1 , GINGF , HGF , NS4 , SOS-1

Background

This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-SOS1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64852

GTX64852 IHC-P Image

IHC-P analysis of rat heart tissue using GTX64852 SOS1 antibody.
Blue : DAPI
Dilution : 1:100

Anti-SOS1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64852

GTX64852 IHC-P Image

IHC-P analysis of rat brain tissue using GTX64852 SOS1 antibody.
Blue : DAPI
Dilution : 1:100

Anti-SOS1 antibody used in Western Blot (WB). GTX64852

GTX64852 WB Image

WB analysis of various sample lysates using GTX64852 SOS1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399