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SOX2 antibody [SOX2/1792]

Anti-SOX2 antibody [SOX2/1792] used in Western Blot (WB). GTX35087
Anti-SOX2 antibody [SOX2/1792] used in IHC (Paraffin sections) (IHC-P). GTX35087
Anti-SOX2 antibody [SOX2/1792] used in IHC (Paraffin sections) (IHC-P). GTX35087
Anti-SOX2 antibody [SOX2/1792] used in IHC (Paraffin sections) (IHC-P). GTX35087
Anti-SOX2 antibody [SOX2/1792] used in IHC (Paraffin sections) (IHC-P). GTX35087
Anti-SOX2 antibody [SOX2/1792] used in Protein Array (Protein Array). GTX35087

Cat. No. GTX35087

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 SOX2/1792

Isotype

 IgG2b

Application

 WB, IHC-P, ELISA, Protein Array

Reactivity

 Human, Mouse
Package
100 μg ($529)
See all SOX2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2μg/ml
IHC-P 1-2μg/ml for 30 min at RT
ELISA 2-4μg/ml (for coating)
Protein Array Assay dependent

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.

ELISA
For ELISA coating, recommend using BSA-free format (please contact us for PBS only format).
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment (within aa176-305) of human SOX2 protein (exact sequence is proprietary)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ANOP3 , MCOPS3 , SOX2 , SRYbox 2 , SRY-box transcription factor 2

Cellular Localization

Nucleus

Background

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-SOX2 antibody [SOX2/1792] used in Western Blot (WB). GTX35087

GTX35087 WB Image

WB analysis of recombinant SOX2 protein fragment and NCCIT cell lysates using GTX35087 SOX2 antibody [SOX2/1792].

Anti-SOX2 antibody [SOX2/1792] used in IHC (Paraffin sections) (IHC-P). GTX35087

GTX35087 IHC-P Image

IHC-P analysis of mouse intestine tissue using GTX35087 SOX2 antibody [SOX2/1792].

Anti-SOX2 antibody [SOX2/1792] used in IHC (Paraffin sections) (IHC-P). GTX35087

GTX35087 IHC-P Image

IHC-P analysis of mouse stomach tissue using GTX35087 SOX2 antibody [SOX2/1792].

Anti-SOX2 antibody [SOX2/1792] used in IHC (Paraffin sections) (IHC-P). GTX35087

GTX35087 IHC-P Image

IHC-P analysis of human lung carcinoma tissue using GTX35087 SOX2 antibody [SOX2/1792].

Anti-SOX2 antibody [SOX2/1792] used in IHC (Paraffin sections) (IHC-P). GTX35087

GTX35087 IHC-P Image

IHC-P analysis of human cervical carcinoma tissue using GTX35087 SOX2 antibody [SOX2/1792].

Anti-SOX2 antibody [SOX2/1792] used in Protein Array (Protein Array). GTX35087

GTX35087 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using SOX2 Mouse Monoclonal Antibody (SOX2/1792). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529