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SOX4 antibody [SOX4/2540]

Anti-SOX4 antibody [SOX4/2540] used in IHC (Paraffin sections) (IHC-P). GTX17992
Anti-SOX4 antibody [SOX4/2540] used in IHC (Paraffin sections) (IHC-P). GTX17992

Cat. No. GTX17992

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 SOX4/2540

Isotype

 IgG2b

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all SOX4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2μg/ml for 30 minutes at RT

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human SOX4 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

EVI16 , SOX4 , SRYbox 4 , SRY-box transcription factor 4

Cellular Localization

Nucleus

Background

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-SOX4 antibody [SOX4/2540] used in IHC (Paraffin sections) (IHC-P). GTX17992

GTX17992 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX17992 SOX4 antibody [SOX4/2540].

Anti-SOX4 antibody [SOX4/2540] used in IHC (Paraffin sections) (IHC-P). GTX17992

GTX17992 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX17992 SOX4 antibody [SOX4/2540].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529