*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
NT2D1 , IMR32 , U87-MG , MCF-7
Mouse, Rat, Zebrafish, Bovine, Chicken, Pig, Xenopus laevis, Chimpanzee(>80% identity)
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Recombinant protein encompassing a sequence within the center region of human SPAG6. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Sperm Associated Antigen 6,Ct141,Repro-Sa-1,Pf16,Spag6
Cytoplasm , cytoskeleton , Cell projection , cilium , flagellum
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined. [provided by RefSeq]
GTX115258 WB Image
Sample (30 ug of whole cell lysate)
7.5% SDS PAGE
GTX115258 diluted at 1:1000
GTX115258 IHC-P Image
Immunohistochemical analysis of paraffin-embedded H441 xenograft, using SPAG6(GTX115258) antibody at 1:500 dilution.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min