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SPPL2B antibody, N-term

Anti-SPPL2B antibody, N-term used in Western Blot (WB). GTX46586
Anti-SPPL2B antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX46586

Cat. No. GTX46586

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
50 μg ($419)
See all SPPL2B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

65 kDa. ( Note )

Positive Control

Jurkat

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human SPPL2B

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

signal peptide peptidase like 2B , IMP-4 , IMP4 , PSH4 , PSL1

Cellular Localization

Cell membrane,Golgi apparatus membrane,Lysosome membrane,Endosome membrane,Membrane

Background

This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-SPPL2B antibody, N-term used in Western Blot (WB). GTX46586

GTX46586 WB Image

WB analysis of Jurkat cells using GTX46586 SPPL2B antibody at 1μg/ml.

Anti-SPPL2B antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX46586

GTX46586 IHC-P Image

IHC-P analysis of human kidney tissue using GTX46586 SPPL2B antibody at 4.0-8.0μg/ml.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419