*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
A549 Cell Lysate(GTX27910) , Human Lung Tissue Slide , HeLa Cell Lysate
At least two isoforms of SPT1 are known to exist; this antibody will detect only isoform a. SPT1 antibody is predicted to not cross-react with SPT2.
PBS with 0.02% sodium azide.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
SPTLC1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SPTLC1.The immunogen is located within amino acids 380 - 430 of SPTLC1.
Purified by antigen-affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
serine palmitoyltransferase long chain base subunit 1 , HSAN1 , HSN1 , LBC1 , LCB1 , SPT1 , SPTI
Endoplasmic reticulum membrane
Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GTX32011 IHC-P Image
IHC-P analysis of human lung tissue using GTX32011 SPTLC1 antibody.
Working concentration : 5 μg/ml
GTX32011 WB Image
WB analysis of (A) A549 and (B) HeLa cell lysate using GTX32011 SPTLC1 antibody.
Working concentration : 1 μg/ml