GeneTex
United States (US)

SPTLC1 antibody

GTX32895_20180530_WB_18121410_608.jpg
GTX32895_20180530_IHC-P_18121410_749.jpg
GTX32895_20180530_IHC-P_1_18121410_380.jpg

Cat No. GTX32895

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

53 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 37-310 of human SPTLC1 (NP_006406.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Serine Palmitoyltransferase Long Chain Base Subunit 1,Hsan1,Hsn1,Lbc1,Lcb1,Spt1,Spti,Sptlc1

Background

Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX32895_20180530_WB_18121410_608.jpg

GTX32895 WB Image

WB analysis of various samples using GTX32895 SPTLC1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX32895_20180530_IHC-P_18121410_749.jpg

GTX32895 IHC-P Image

IHC-P analysis of human kidney tissue using GTX32895 SPTLC1 antibody.
Dilution : 1:100

GTX32895_20180530_IHC-P_1_18121410_380.jpg

GTX32895 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX32895 SPTLC1 antibody.
Dilution : 1:100

Package List Price ($)
$ 329