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SPTLC1 antibody

Anti-SPTLC1 antibody used in Western Blot (WB). GTX32895
Anti-SPTLC1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32895
Anti-SPTLC1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32895

Cat No. GTX32895

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 37-310 of human SPTLC1 (NP_006406.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

serine palmitoyltransferase long chain base subunit 1 , HSAN1 , HSN1 , LBC1 , LCB1 , SPT1 , SPTI

Cellular Localization

Endoplasmic reticulum membrane

Background

This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. [provided by RefSeq, Jul 2013]

Database

DATA IMAGES

Anti-SPTLC1 antibody used in Western Blot (WB). GTX32895

GTX32895 WB Image

WB analysis of various samples using GTX32895 SPTLC1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-SPTLC1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32895

GTX32895 IHC-P Image

IHC-P analysis of human kidney tissue using GTX32895 SPTLC1 antibody.
Dilution : 1:100

Anti-SPTLC1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32895

GTX32895 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX32895 SPTLC1 antibody.
Dilution : 1:100

REFERENCE

There are currently no references for SPTLC1 antibody (GTX32895). Be the first to share your publications with this product.

REVIEW

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Package List Price ($)
$ 329