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SR-BI antibody

Anti-SR-BI antibody used in IHC (Paraffin sections) (IHC-P). GTX20003
Anti-SR-BI antibody used in Western Blot (WB). GTX20003
Anti-SR-BI antibody used in Flow cytometry (FACS). GTX20003
Anti-SR-BI antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX20003
Anti-SR-BI antibody used in Western Blot (WB). GTX20003

Cat. No. GTX20003

Reference 4

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IHC-Fr, FACS, IP, Neutralizing/Inhibition

Reactivity

 Human, Mouse, Rat, Bovine, Hamster, Mustelid, Schistosoma japonicum, Primate
Package
100 μl ($449)
See all SR-BI products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000 - 1:5000
ICC/IF 1:50 - 1:1000
IHC-P 2.5 - 5 μg/ml
IHC-Fr Assay dependent
FACS 1:400
IP 1:10 - 1:500
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

A C-terminal peptide containing residues from mouse SR-BI (within residues 450-509). [UniProt# Q61009]

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_372955

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

scavenger receptor class B, member 1 , AI120173 , CD36 , Cd36l1 , Chohd1 , Cla-1 , Cla1 , D5Ertd460e , Hdlq1 , Hlb398 , SR-B1 , SR-BI , SRBI , Srb1 , mSR-BI

Cellular Localization

Cell membrane

Background

Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (By similarity). Plays an important role in the uptake of HDL cholesteryl ester.

Database

Research Area

DATA IMAGES

Anti-SR-BI antibody used in IHC (Paraffin sections) (IHC-P). GTX20003

GTX20003 IHC-P Image

IHC-P analysis of human liver tissue using GTX20003 SR-BI antibody.
Dilution : 1:300

Anti-SR-BI antibody used in Western Blot (WB). GTX20003

GTX20003 WB Image

WB analysis of mouse liver tissue lysate using GTX20003 SR-BI antibody.

Anti-SR-BI antibody used in Flow cytometry (FACS). GTX20003

GTX20003 FACS Image

FACS analysis of HeLa cells using GTX20003 SR-BI antibody. M1 is defined by unstained cells.
Purple : primary antibody
Dilution : 1:400

Anti-SR-BI antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX20003

GTX20003 ICC/IF Image

ICC/IF analysis of HeLa cells (fixed and permeabilized with MeOH) using GTX20003 SR-BI antibody.
Green : primary antibody
Red : Tubulin
Blue : DAPI
Dilution : 2 μg/ml

Anti-SR-BI antibody used in Western Blot (WB). GTX20003

GTX20003 WB Image

WB analysis of HeLa cell lysate using GTX20003 SR-BI antibody.

REFERENCE

Application Reference

Ruhela D et al. Brain Behav Immun Health 2021; 18 : 100398 Astrocyte-derived microparticles initiate a neuroinflammatory cycle due to carbon monoxide poisoning.
Reactivity : Mouse
Ruhela D et al. Brain, Behavior, & Immunity - Health 2021; 18 : 100398 Astrocyte-derived microparticles initiate a neuroinflammatory cycle due to carbon monoxide poisoning.
Koide N et al. Biochim Biophys Acta Mol Cell Res 2021; 1868 (7) : 119043 Binding of liposomes composed of phosphatidylcholine to scavenger receptor class B type 1 and its modulation by phosphatidic acid in HEK293T cells.
Stylianou IM et al. PLoS One 2009; 4 (8) : e6521 Novel ENU-induced point mutation in scavenger receptor class B, member 1, results in liver specific loss of SCARB1 protein.
Application : WB
Reactivity : Mouse
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 449