APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:1000 - 1:5000 |
1:50 - 1:1000 |
2.5 - 5 μg/ml |
Assay dependent |
1:10 - 1:1000 |
1:10 - 1:500 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Mouse
Immunogen
A C-terminal peptide containing residues from mouse SR-BI (within residues 450-509). [UniProt# Q61009]
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
scavenger receptor class B, member 1 , AI120173 , CD36 , Cd36l1 , Chohd1 , Cla-1 , Cla1 , D5Ertd460e , Hdlq1 , Hlb398 , SR-B1 , SR-BI , SRBI , Srb1 , mSR-BI
Cellular Localization
Cell membrane
Background
Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (By similarity). Plays an important role in the uptake of HDL cholesteryl ester.
Database
Research Area
DATA IMAGES
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GTX20396 FACS Image
FACS (Intracellular staining) analysis of HeLa cells using GTX20396 SR-BI antibody. Blue : Primary antibody Orange : isotype control Dilution : 2 μg/mL Fixation : 4% PFA Permibilization : 0.1% saponin
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GTX20396 ICC/IF Image
ICC/IF analysis of HeLa cells using GTX20396 SR-BI antibody. Green : primary antibody Red : Tubulin Blue : DAPI Dilution : 2 μg/ml
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GTX20396 IHC-P Image
IHC-P analysis of mouse liver tissue using GTX20396 SR-BI antibody. Dilution : 1:300
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GTX20396 WB Image
WB analysis of HeLa cell lysate using GTX20396 SR-BI antibody.
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GTX20396 IHC-P Image
IHC-P analysis of human adrenal cortex tissue using GTX20396 SR-BI antibody.
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GTX20396 WB Image
WB analysis of human adrenal tissue using GTX20396 SR-BI antibody.
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GTX20396 WB Image
WB analysis of mouse liver tissue lysate using GTX20396 SR-BI antibody. Loading : 25μg Dilution : 1:1000
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GTX20396 ICC/IF Image
ICC/IF analysis of human fibroblasts using GTX20396 SR-BI antibody. Green : primary antibody Blue : DAPI Dilution : 1:100 Fixation : 4% PFA Permeabilization : 0.2% Tween
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GTX20396 IHC-P Image
IHC-P analysis of mouse liver tissue using GTX20396 SR-BI antibody. Dilution : 1:300
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REFERENCE
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REVIEW
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