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SR-BI antibody

Anti-SR-BI antibody used in IHC (Paraffin sections) (IHC-P). GTX30467
Anti-SR-BI antibody used in IHC (Paraffin sections) (IHC-P). GTX30467
Anti-SR-BI antibody used in Western Blot (WB). GTX30467
Anti-SR-BI antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30467

Cat. No. GTX30467

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IHC-Fr, FACS, IP, Neutralizing/Inhibition

Reactivity

 Human, Mouse, Rat
Package
100 μl ($419)
See all SR-BI products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500
ICC/IF 1:50 - 1:200
IHC-P 1:100
IHC-Fr Assay dependent
FACS Assay dependent
IP 1:100
Neutralizing/Inhibition 1:500 - 1000
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

Serum

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Mouse

Immunogen

Adenovirus encoding mouse SR-BI. [UniProt# Q61009]

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_372960

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Background

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.

Research Area

DATA IMAGES

Anti-SR-BI antibody used in IHC (Paraffin sections) (IHC-P). GTX30467

GTX30467 IHC-P Image

IHC-P analysis of human adrenal gland tissue using GTX30467 SR-BI antibody.
Dilution : 1:100

Anti-SR-BI antibody used in IHC (Paraffin sections) (IHC-P). GTX30467

GTX30467 IHC-P Image

IHC-P analysis of human adrenal gland tissue using GTX30467 SR-BI antibody.
Dilution : 1:100

Anti-SR-BI antibody used in Western Blot (WB). GTX30467

GTX30467 WB Image

WB analysis of mouse testis tissue using GTX30467 SR-BI antibody.

Anti-SR-BI antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30467

GTX30467 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX30467 SR-BI antibody.
Green : primary antibody
Red : Tubulin
Blue : DAPI

REFERENCE

Application Reference

Dao Thi VL et al. J Biol Chem 2012; 287 (37) : 31242-57 Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps.
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 419