GeneTex
United States (US)

SR-BI antibody

GTX30467_556_IHC-P_18121410_824.jpg
GTX30467_1408_WB_18121410_625.jpg
GTX30467_210_ICC-IF_18121410_100.jpg
GTX30467_557_IHC-P_18121410_183.jpg

Cat No. GTX30467

Reference 1
Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P, IHC-Fr, FACS, IP, Neut
Reactivity Human, Mouse, Rat
See all SR-BI products
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500
ICC/IF 1:50 - 1:200
IHC-P 1:100
IHC-Fr Assay dependent
FACS Assay dependent
IP 1:100
Neut 1:500 - 1000
Not tested in other applications.
PROPERTIES

Form

Liquid

Buffer

Serum, 0.05% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent(Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Adenovirus encoding mouse SR-BI. [UniProt# Q61009]

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

SR BI, SR B1, Scavenger Receptor BI, Scavenger Receptor B1, SRBI, SRB1, Scavenger ReceptorBI, Scavenger ReceptorB1

Background

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.

Research Area

DATA IMAGES
GTX30467_556_IHC-P_18121410_824.jpg

GTX30467 IHC-P Image

IHC-P analysis of human adrenal gland tissue using GTX30467 SR-BI antibody.
Dilution : 1:100
GTX30467_1408_WB_18121410_625.jpg

GTX30467 WB Image

WB analysis of mouse testis tissue using GTX30467 SR-BI antibody.
GTX30467_210_ICC-IF_18121410_100.jpg

GTX30467 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX30467 SR-BI antibody.
Green : primary antibody
Red : Tubulin
Blue : DAPI
GTX30467_557_IHC-P_18121410_183.jpg

GTX30467 IHC-P Image

IHC-P analysis of human adrenal gland tissue using GTX30467 SR-BI antibody.
Dilution : 1:100
REFERENCE

Application Reference

Dao Thi VL et al. J Biol Chem 2012; 287 (37):31242-57 Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps.
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Package List Price ($)
$ 359