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SRC3 antibody [AX15.3]

Anti-SRC3 antibody [AX15.3] used in Western Blot (WB). GTX22782
Anti-SRC3 antibody [AX15.3] used in IHC (Paraffin sections) (IHC-P). GTX22782

Cat. No. GTX22782

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 AX15.3

Isotype

 IgG1

Application

 WB, IHC-P, IP, ChIP assay

Reactivity

 Human
Package
100 μg ($399)
See all SRC3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 2μg/ml
IHC-P 1:10-1:100
IP Assay dependent
ChIP assay Assay dependent
Not tested in other applications.

Calculated MW

155 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

GST fusion protein encoding amino acid residues 605-1294 of human AIB1.

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

nuclear receptor coactivator 3 , ACTR , AIB-1 , AIB1 , CAGH16 , CTG26 , KAT13B , RAC3 , SRC-3 , SRC3 , TNRC14 , TNRC16 , TRAM-1 , bHLHe42 , pCIP

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010]

Database

Research Area

DATA IMAGES

Anti-SRC3 antibody [AX15.3] used in Western Blot (WB). GTX22782

GTX22782 WB Image

WB analysis of MCF-7 cell extract using GTX22782 SRC3 antibody [AX15.3].

Anti-SRC3 antibody [AX15.3] used in IHC (Paraffin sections) (IHC-P). GTX22782

GTX22782 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX22782 SRC3 antibody [AX15.3].
Left : Primary antibody
Right : Negative control without primary antibody
Antigen retrieval : heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer, microwaved for 8-15 minutes
Dilution : 1:20

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399