GeneTex
United States (US)

SRGAP2 antibody, Internal

GTX88045_2456_WB_18122102_458.jpg

Cat No. GTX88045

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.1-0.3μg/ml
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

121 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88045-PEP).

Specificity/Sensitivity

This antibody is expected to recognize isoform a (NP_056141.2).

Predict Reactivity

Mouse, Bovine, Dog(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-KQEDRQTPRSPDST, from the internal region of the protein sequence according to NP_056141.2.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Slit-Robo Rho Gtpase Activating Protein 2,Arhgap34,Fnbp2,Srgap2A,Srgap3,Srgap2

Background

This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogous loci on human chromosome 1, resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Dec 2012]

Database

Research Area

DATA IMAGES
GTX88045_2456_WB_18122102_458.jpg

GTX88045 WB Image

WB analysis of rat Cortical Neuron lysate using GTX88045 SRGAP2 antibody, Internal.
Dilution : 0.1µg/ml
Loading : 35µg protein in RIPA buffer

Package List Price ($)
$ 329