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STAT1 antibody [SM1]

Orthogonal
Anti-STAT1 antibody [SM1] used in Western Blot (WB). GTX23987

Cat. No. GTX23987

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 SM1

Isotype

 IgG2b

Application

 WB, IHC-P, IP

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all STAT1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

87 kDa. ( Note )

Product Note

This antibody recognizes an epitope included within amino acids 721-733 of STAT1.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

STAT1 peptide sequence 721-733 (DNLLPMSPEEFDE).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CANDF7 , IMD31A , IMD31B , IMD31C , ISGF3 , STAT1 , STAT91 , signal transducer and activator of transcription 1

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-STAT1 antibody [SM1] used in Western Blot (WB). GTX23987

GTX23987 WB Image

Orthogonal

WB analysis of human malignant melanoma cells (short-term culture derived from a patient) treated with IFN-gamma (10 ng/ml) and IFN-alpha (1000 IU/ml and 5000 IU/ml) using GTX23987 STAT1 antibody [SM1].
Upper Lane : GTX23991 STAT1 (phospho Ser727) antibody [PSM1]
Lower Lane : GTX23987 STAT1 antibody [SM1]

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399