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STAT1 (phospho Tyr701) antibody

Orthogonal
Anti-STAT1 (phospho Tyr701) antibody used in Western Blot (WB). GTX50118
Anti-STAT1 (phospho Tyr701) antibody used in Western Blot (WB). GTX50118
Anti-STAT1 (phospho Tyr701) antibody used in IHC (Paraffin sections) (IHC-P). GTX50118
Anti-STAT1 (phospho Tyr701) antibody used in Western Blot (WB). GTX50118
Anti-STAT1 (phospho Tyr701) antibody used in Western Blot (WB). GTX50118

Cat. No. GTX50118

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all STAT1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

87 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around phosphorylation site of tyrosine 701 (T-G-Y(p)-I-K) derived from human STAT1.

Purification

Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Conjugation

Unconjugated

RRID

AB_11169308

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

signal transducer and activator of transcription 1 , CANDF7 , IMD31A , IMD31B , IMD31C , ISGF-3 , STAT91

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-STAT1 (phospho Tyr701) antibody used in Western Blot (WB). GTX50118

GTX50118 WB Image

Orthogonal

WB analysis of extracts from MEF cells untreated or treated with interferon-ɤ (IFNɤ) using GTX50118 STAT1 (phospho Tyr701) antibody.

Anti-STAT1 (phospho Tyr701) antibody used in Western Blot (WB). GTX50118

GTX50118 WB Image

Orthogonal

WB analysis of extracts from HeLa cells treated with IFNa or calf intestinal phosphatase (CIP) using GTX50118 STAT1 (phospho Tyr701) antibody.

Anti-STAT1 (phospho Tyr701) antibody used in IHC (Paraffin sections) (IHC-P). GTX50118

GTX50118 IHC-P Image

Orthogonal

IHC-P analysis of human breast carcinoma tissue using GTX50118 STAT1 (phospho Tyr701) antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide

Anti-STAT1 (phospho Tyr701) antibody used in Western Blot (WB). GTX50118

GTX50118 WB Image

Orthogonal

The data was published in the journal PLoS One in 2015. PMID: 25646764

Anti-STAT1 (phospho Tyr701) antibody used in Western Blot (WB). GTX50118

GTX50118 WB Image

Orthogonal

The data was published in the journal PLoS One in 2015. PMID: 25646764

REFERENCE

Application Reference

Kanazawa N et al. Nat Commun 2021; 12 (1) : 6819 Heterozygous missense variant of the proteasome subunit β-type 9 causes neonatal-onset autoinflammation and immunodeficiency.
Application : IHC-P
Reactivity : Human
Chang JT et al. PLoS One 2015; 10 (2) : e0116158 genome and infection characteristics of human parechovirus type 1: the interplay between viral infection and type i * antiviral system.
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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399