APPLICATION
Application Note
Blocking peptide for rabbit polyconal antibody to STAT2(GTX27965).
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, BSA
Preservative
0.1% Sodium azide
Storage
Keep as concentrated solution, aliquot and store at 4ºC.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Region/Sequence
Peptide mapping to the carboxy terminus of human Stat2 p113.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
signal transducer and activator of transcription 2 , IMD44 , ISGF-3 , P113 , STAT113
Cellular Localization
Cytoplasm , Nucleus
Background
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Database
Research Area
REFERENCE
There are currently no references for STAT2 peptide (GTX27999). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for STAT2 peptide (GTX27999). Be the first to share your experience with this product.