GeneTex

  • Country / Location Selection

United States (US)

STAT3 antibody [3F4]

Anti-STAT3 antibody [3F4] used in IHC (Paraffin sections) (IHC-P). GTX34234
Anti-STAT3 antibody [3F4] used in Western Blot (WB). GTX34234
Anti-STAT3 antibody [3F4] used in IHC (Paraffin sections) (IHC-P). GTX34234

Cat. No. GTX34234

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3F4

Isotype

 IgG1

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all STAT3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000-1:2000
IHC-P 1:100-1:200
Not tested in other applications.

Calculated MW

88 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.5% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Protein

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ADMIO,ADMIO1,APRF,HIES,STAT3,signal transducer and activator of transcription 3

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-STAT3 antibody [3F4] used in IHC (Paraffin sections) (IHC-P). GTX34234

GTX34234 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX34234 STAT3 antibody [3F4].
Dilution : 1:200

Anti-STAT3 antibody [3F4] used in Western Blot (WB). GTX34234

GTX34234 WB Image

WB analysis of (1) rat heart tissue, (2)mouse heart tissue, (3) HeLa lysates using GTX34234 STAT3 antibody [3F4].
Dilution : 1:2000

Anti-STAT3 antibody [3F4] used in IHC (Paraffin sections) (IHC-P). GTX34234

GTX34234 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX34234 STAT3 antibody [3F4].
Dilution : 1:200

REFERENCE

There are currently no references for STAT3 antibody [3F4] (GTX34234). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for STAT3 antibody [3F4] (GTX34234). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399