GeneTex
United States (US)

STAT5 antibody

GTX37534_20190129_IHC-P_19012901_319.jpg

Cat No. GTX37534

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P 1:400-800
Not tested in other applications.

Calculated MW

91 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.01M TBS pH7.4, 0.5% BSA, 0.015% ProClin™ 300, 25% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 71-150 amino acids of human STAT5

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

MGF,STAT5

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
DATA IMAGES
GTX37534_20190129_IHC-P_19012901_319.jpg

GTX37534 IHC-P Image

IHC-P analysis of human lung carcinoma tissue using GTX37534 STAT5 antibody.
Fixation : 4% PFA
Antigen retireval : boiling with citrate buffer
Dilution : 1:200

REFERENCE
Package List Price ($)
$ 219