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STAT5B antibody

Anti-STAT5B antibody used in Western Blot (WB). GTX32898
Anti-STAT5B antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32898

Cat No. GTX32898

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF

Reactivity

Human, Rat
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

90 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 40-280 of human STAT5B (NP_036580.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

signal transducer and activator of transcription 5B , STAT5

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-STAT5B antibody used in Western Blot (WB). GTX32898

GTX32898 WB Image

WB analysis of various samples using GTX32898 STAT5B antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-STAT5B antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32898

GTX32898 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX32898 STAT5B antibody.
Blue : DAPI

REFERENCE

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REVIEW

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Package List Price ($)
$ 329