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STAT6 antibody [7D3]

Anti-STAT6 antibody [7D3] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX82814
Anti-STAT6 antibody [7D3] used in Western Blot (WB). GTX82814

Cat. No. GTX82814

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 7D3

Isotype

 IgG1

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Mouse, Rat, Monkey
Package
100 μl ($399)
See all STAT6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ICC/IF 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

94 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human STAT6 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

signal transducer and activator of transcription 6 , D12S1644 , IL-4-STAT , STAT6B , STAT6C

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES

Anti-STAT6 antibody [7D3] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX82814

GTX82814 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX82814 STAT6 antibody [7D3].
Green : STAT6
Blue: DRAQ5 fluorescent DNA dye
Red: Actin filaments

Anti-STAT6 antibody [7D3] used in Western Blot (WB). GTX82814

GTX82814 WB Image

WB analysis of HEK293 (1), NIH3T3 (2), MCF-7 (3), Raw246.7 (4) and PC-12 (5) cell lysate using GTX82814 STAT6 antibody [7D3].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399