GeneTex

  • Country / Location Selection

United States (US)

STAT6 antibody

Cat. No. GTX82421

Host

 Chicken

Clonality

 Polyclonal

Isotype

 IgY

Application

 WB

Reactivity

 Human
Package
50 μg ($519)
See all STAT6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500
Not tested in other applications.

Calculated MW

94 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Immunogen Sequence: GI # 23397678, sequence 61-275 Recombinant signal transducer and activator of transcription 6

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

signal transducer and activator of transcription 6 , D12S1644 , IL-4-STAT , STAT6B , STAT6C

Cellular Localization

Cytoplasm,Nucleus

Background

Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors. STAT family members are phosphorylated by the receptor associated kinases. and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L). which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells. expression of cell surface markers. and class switch of immunoglobulins.

Database

Research Area

REFERENCE

There are currently no references for STAT6 antibody (GTX82421). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for STAT6 antibody (GTX82421). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 519