APPLICATION
Application Note
Blocking peptide for rabbit polyconal antibody to STAT6(GTX22424).
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, BSA
Preservative
0.1% Sodium azide
Storage
Store this product at 4ºC, DO NOT FREEZE. The product is stable for one year from the date of shipment.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Region/Sequence
Peptide mapping to the carboxy terminus of human Stat6.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
signal transducer and activator of transcription 6 , D12S1644 , IL-4-STAT , STAT6B , STAT6C
Cellular Localization
Cytoplasm , Nucleus
Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Database
Research Area
REFERENCE
There are currently no references for STAT6 peptide (GTX22425). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for STAT6 peptide (GTX22425). Be the first to share your experience with this product.