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STEAP3 antibody

Anti-STEAP3 antibody used in IHC (Paraffin sections) (IHC-P). GTX85434
Anti-STEAP3 antibody used in IHC (Paraffin sections) (IHC-P). GTX85434
Anti-STEAP3 antibody used in Western Blot (WB). GTX85434

Cat. No. GTX85434

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all STEAP3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

55 kDa. ( Note )

Positive Control

HeLa Cell Lysate

Product Note

This STEAP3 antibody does not cross-react with other STEAP proteins.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

STEAP3 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human STEAP3.The immunogen is located within the first 50 amino acids of STEAP3.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

STEAP3 metalloreductase , AHMIO2 , STMP3 , TSAP6 , dudlin-2 , dudulin-2 , pHyde

Cellular Localization

Endosome membrane

Background

The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells. This STEAP3 antibody does not cross-react with other STEAP proteins.

Database

Research Area

DATA IMAGES

Anti-STEAP3 antibody used in IHC (Paraffin sections) (IHC-P). GTX85434

GTX85434 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX85434 STEAP3 antibody.
Working concentration : 20 μg/ml

Anti-STEAP3 antibody used in IHC (Paraffin sections) (IHC-P). GTX85434

GTX85434 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX85434 STEAP3 antibody.
Working concentration : 2.5 μg/ml

Anti-STEAP3 antibody used in Western Blot (WB). GTX85434

GTX85434 WB Image

WB analysis of HeLa cell lysate using GTX85434 STEAP3 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399