*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
STEA3 Antibody detects endogenous levels of total STEA3 protein.
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
The antiserum was produced against synthesized peptide derived from human STEAP3.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
hTSAP6, EC1.16.1., Six-transmembrane epithelial antigen of prostate 3, Dudulin2, pHyde, STEA3, Tumor suppressoractivated pathway protein 6, Sixtransmembrane epithelial antigen of prostate3, EC 1.16.1.-, Tumor suppressor-activated pathway protein 6, Sixtransmembrane epithelial antigen of prostate 3, Tumor suppressoractivated pathway protein6, hpHyde, EC 1.16.1.
Localizes to vesicular-like structures at the plasma membrane and around the nucleus.
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NAD(+) as acceptor (By similarity). May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.