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STING antibody [MSVA-515M] HistoMAX™

Recombinant antibody HistoMAX
Anti-STING antibody [MSVA-515M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04484
Anti-STING antibody [MSVA-515M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04484
Anti-STING antibody [MSVA-515M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04484

Cat. No. GTX04484

Host

Mouse

Clonality

Monoclonal

Clone Name

MSVA-515M

Isotype

IgG2c

Application

IHC-P

Reactivity

Human
Package
500 μl ($679),
100 μl ($299)
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.

Not tested in other applications.

Calculated MW

42 kDa. ( Note )

Positive Control

Adrenal gland: Endothelial cells and macrophages should show a moderate to strong STING positivity.

Negative Control

Adrenal gland: Adrenocortical and medullary cells should not show STING staining (Note: in case of tissue damage aberrant STING staining may occur).

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA (Please contact us for PBS only format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment (around aa190-290) of human TMEM173 protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transmembrane protein 173 , ERIS , MITA , MPYS , NET23 , SAVI , STING , STING-beta , hMITA , hSTING

Cellular Localization

Endoplasmic reticulum membrane , Mitochondrion outer membrane , Cell membrane , Cytoplasm, perinuclear region , Cytoplasm

Background

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Database

Research Area

DATA IMAGES

Anti-STING antibody [MSVA-515M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04484

GTX04484 IHC-P Image

IHC-P analysis of human pancreatic ductal adenocarcinoma tissue section using GTX04484 STING antibody [MSVA-515M] HistoMAX™.
Ductal adenocarcinoma with strong MPYS positivity of all tumor cells MPYS immunohistochemistry.

Anti-STING antibody [MSVA-515M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04484

GTX04484 IHC-P Image

IHC-P analysis of human adrenal gland tissue section using GTX04484 STING antibody [MSVA-515M] HistoMAX™.
MPYS staining of endothelial cells and of macrophages MPYS immunohistochemistry.

Anti-STING antibody [MSVA-515M] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04484

GTX04484 IHC-P Image

IHC-P analysis of human appendix mucosa tissue section using GTX04484 STING antibody [MSVA-515M] HistoMAX™.
MPYS staining of inflammatory cells predominates in the interfollicular zone MPYS immunohistochemistry.

REFERENCE

There are currently no references for STING antibody [MSVA-515M] HistoMAX™ (GTX04484). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for STING antibody [MSVA-515M] HistoMAX™ (GTX04484). Be the first to share your experience with this product.
Package List Price ($)
$ 679
$ 299