APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 0.1-0.5μg/ml |
| 0.5-1μg/ml |
| Assay dependent |
| 0.5-1μg/ml |
| 1-3μg/1x10⁶ cells |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄
Preservative
0.05mg Sodium Azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human SUR1
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
ABC36,ABCC8,ATP binding cassette subfamily C member 8,HHF1,HI,HRINS,MRP8,PHHI,SUR,SUR1,SUR1delta2,TNDM2
Cellular Localization
Membrane
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
Database
Research Area
DATA IMAGES
|
GTX04855 WB Image
WB analysis of various samples using GTX04855 SUR1 antibody.
Lane 1 : Human placenta tissue lysate
Lane 2 : Rat brain tissue lysate
Lane 3 : Mouse brain tissue lysate
Loading : 50μg
Dilution : 0.5 μg/mL
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GTX04855 FACS Image
FACS analysis of A431 cells using GTX04855 SUR1 antibody.
Blue : Primary antibody
Green : Isotype control
Red : Unlabelled sample
Dilution : 1μg/1x10⁶ cells
|
|
|
GTX04855 WB Image
WB analysis of various samples using GTX04855 SUR1 antibody.
Lane 1 : Human placenta tissue lysate
Lane 2 : Rat brain tissue lysate
Lane 3 : Mouse brain tissue lysate
Loading : 50μg
Dilution : 0.5 μg/mL
|
|
|
GTX04855 FACS Image
FACS analysis of A431 cells using GTX04855 SUR1 antibody.
Blue : Primary antibody
Green : Isotype control
Red : Unlabelled sample
Dilution : 1μg/1x10⁶ cells
|
REFERENCE
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REVIEW
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