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Sclerostin antibody, Internal

Anti-Sclerostin antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX81933
Anti-Sclerostin antibody, Internal used in Western Blot (WB). GTX81933

Cat. No. GTX81933

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
400 μl ($399)
See all Sclerostin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:10-1:50
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 134-163 amino acids from the Central region of human SOST.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sclerostin , CDD , DAND6 , SOST1 , VBCH

Background

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Sclerostin antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX81933

GTX81933 IHC-P Image

IHC-P analysis of human hepatocarcinoma using GTX81933 Sclerostin antibody, Internal.

Anti-Sclerostin antibody, Internal used in Western Blot (WB). GTX81933

GTX81933 WB Image

WB analysis of human kidney and liver tissue lysate using GTX81933 Sclerostin antibody, Internal.
Loading : 35ug per lane
Dilution : 1:1000

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399