GeneTex

  • Country / Location Selection

United States (US)

Serotonin N-AT antibody

Anti-Serotonin N-AT antibody used in IHC (Frozen sections) (IHC-Fr). GTX23506
Anti-Serotonin N-AT antibody used in Western Blot (WB). GTX23506

Cat. No. GTX23506

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-Fr

Reactivity

 Rat
Package
50 μg ($399)
See all Serotonin N-AT products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 μg/ml
IHC-Fr 5-10 μg/ml
Not tested in other applications.

Calculated MW

23 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Synthetic Peptide: C(195) H T F L R R N S G C(205)

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

aralkylamine N-acetyltransferase , AA-NAT , Nat4

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. [provided by RefSeq, Feb 2014]

Database

Research Area

DATA IMAGES

Anti-Serotonin N-AT antibody used in IHC (Frozen sections) (IHC-Fr). GTX23506

GTX23506 IHC-Fr Image

IHC-Fr analysis of adult rat pineal tissue using GTX23506 Serotonin N-AT antibody.
Permeabilization : 0.3% Triton X-100 (TBST)
Dilution : 5-10 μg/ml

Anti-Serotonin N-AT antibody used in Western Blot (WB). GTX23506

GTX23506 WB Image

WB analysis of transfected 293T cell lysate using GTX23506 Serotonin N-AT antibody.

REFERENCE

There are currently no references for Serotonin N-AT antibody (GTX23506). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Serotonin N-AT antibody (GTX23506). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399