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Serotonin N-AT antibody

Anti-Serotonin N-AT antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30289
Anti-Serotonin N-AT antibody used in Western Blot (WB). GTX30289

Cat No. GTX30289

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF

Reactivity

Human, Primate
Package
100 μl ($379)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
ICC/IF 1:200
Not tested in other applications.

Calculated MW

23 kDa. ( Note )

Product Note

We do not recommend use of this product for Rat,Zebrafish,Bovine,Chicken samples.

PROPERTIES

Form

Liquid

Buffer

0.1N Glacial Acetic acid, 0.1% BSA, neutralized using 10x PBS

Preservative

0.05% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human Serotonin N-acetyltransferase [UniProt# Q16613]

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

aralkylamine N-acetyltransferase , DSPS , SNAT

Cellular Localization

Cytoplasm

Background

Arylalkylamine N-acetyltransferase belongs to the superfamily of acetyltransferases. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for seasonal reproduction, modulates the function of the circadian clock in the suprachiasmatic nucleus, and influences activity and sleep. This enzyme is rapidly inactivated when animals are exposed to light at night. This protein is 80% identical to sheep and rat AA-NAT. Arylalkylamine N-acetyltransferase may contribute a multifactorial genetic diseases such as altered behavior in sleep/wake cycle. [provided by RefSeq]

Database

  • Gene ID: 15 AANAT
  • UniProt: Q16613 AANAT

Research Area

DATA IMAGES

Anti-Serotonin N-AT antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30289

GTX30289 ICC/IF Image

ICC/IF analysis of FSK-treated 1E7 and COS-7 cells for 3hrs using GTX30289 Serotonin N-AT antibody.
Fixation : 2.5% glutaraldehyde

Anti-Serotonin N-AT antibody used in Western Blot (WB). GTX30289

GTX30289 WB Image

WB analysis of 1E7 cell, human pineal lysate, and bacterially expressed Serotonin N-AT using GTX30289 Serotonin N-AT antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Thimerosal.pdf
Package List Price ($)
$ 379