GeneTex
United States (US)

Serotonin N-AT antibody

GTX30289_201_ICC-IF_18121410_287.jpg
GTX30289_1385_WB_18121410_904.jpg

Cat No. GTX30289

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Primate
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
ICC/IF 1:200
Not tested in other applications.

Calculated MW

23 kDa. ( Note )

Specificity/Sensitivity

This product does not react with Rat,Zebrafish,Bovine,Chicken.
PROPERTIES

Form

Liquid

Buffer

0.1N glacial acetic acid, 0.1% BSA, neutralized using 10x PBS, 0.05% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human Serotonin N-acetyltransferase [UniProt# Q16613]

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

DSPS antibody , SNAT antibody

Cellular Localization

Cytoplasm

Background

Arylalkylamine N-acetyltransferase belongs to the superfamily of acetyltransferases. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for seasonal reproduction, modulates the function of the circadian clock in the suprachiasmatic nucleus, and influences activity and sleep. This enzyme is rapidly inactivated when animals are exposed to light at night. This protein is 80% identical to sheep and rat AA-NAT. Arylalkylamine N-acetyltransferase may contribute a multifactorial genetic diseases such as altered behavior in sleep/wake cycle. [provided by RefSeq]

Database

DATA IMAGES
GTX30289_201_ICC-IF_18121410_287.jpg

GTX30289 ICC/IF Image

ICC/IF analysis of FSK-treated 1E7 and COS-7 cells for 3hrs using GTX30289 Serotonin N-AT antibody.
Fixation : 2.5% glutaraldehyde

GTX30289_1385_WB_18121410_904.jpg

GTX30289 WB Image

WB analysis of 1E7 cell, human pineal lysate, and bacterially expressed Serotonin N-AT using GTX30289 Serotonin N-AT antibody.

Package List Price ($)
$ 339