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Serum Amyloid A antibody [115]

Cat No. GTX20687

Host Mouse
Clonality Monoclonal
Clone Name 115
Isotype IgG1
Application WB, IHC-P, ELISA
Reactivity Human
Package
100 μg ($319)
APPLICATION

Application Note

For ELISA: Use at a concentration of 0.3 μg/ml. For WB: Use at a concentration of 0.1-0.5 μg/ml. Optimal dilutions/concentrations should be determined by the researcher.

Specificity/Sensitivity

Reacts with natural and recombinant human Serum Amyloid A (SAA) and does not cross-react with other human cytokines or growth factors tested such as IL-1beta, IL-8, MCAF, TGF-beta and EGF.
PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.2 containing no preservatives

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Highly purified recombinant human serum amyloid A (MW: 12 kDa)

Purification

Protein G affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Serum Amyloid A1,Pig4,Saa,Saa2,Tp53I4,Saa1

Background

The serum amyloid A (SAA) family comprises a number of differentially expressed lipoproteins, acute-phase SAA1 and SAA2, the former being a major component in plasma, and constitutive SAA's (C-SAAs). Although the liver is the primary site of synthesis of both SAA types, extrhepatic production has been reported. The in-vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed it's importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations. SAA rises earlier and more sharply than CRP.

Research Area

REFERENCE
REVIEW
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