Serum Amyloid A antibody [115]

Name: Serum Amyloid A antibody [115]
Brand: GeneTex
SKU: GTX20687
Price: 339.00 USD
Rating: 5 (1 reviews)

Cat No. GTX20687

Reference 2

Host	Mouse
Clonality	Monoclonal
Clone Name	115
Isotype	IgG1
Application	WB, IHC-P, ELISA
Reactivity	Human
Package	100 μg ($339)

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Datasheet
Reference

APPLICATION

Application Note

For ELISA: Use at a concentration of 0.3 μg/ml. For WB: Use at a concentration of 0.1-0.5 μg/ml. Optimal dilutions/concentrations should be determined by the researcher.

Product Note

Reacts with natural and recombinant human Serum Amyloid A (SAA) and does not cross-react with other human cytokines or growth factors tested such as IL-1beta, IL-8, MCAF, TGF-beta and EGF.

PROPERTIES

Form

Liquid

Buffer

PBS pH7.2

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Highly purified recombinant human serum amyloid A (MW: 12 kDa)

Purification

Protein G affinity purified

Conjugation

Unconjugated

RRID

AB_367632

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Serum Amyloid A1 , Pig4 , Saa , Saa2 , Tp53I4 , Saa1

Background

The serum amyloid A (SAA) family comprises a number of differentially expressed lipoproteins, acute-phase SAA1 and SAA2, the former being a major component in plasma, and constitutive SAA's (C-SAAs). Although the liver is the primary site of synthesis of both SAA types, extrhepatic production has been reported. The in-vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed it's importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations. SAA rises earlier and more sharply than CRP.

Research Area

REFERENCE

Application Reference

Lin CY et al. Mol Oncol 2018; 12 (5) : 756-771 Serum amyloid A1 in combination with integrin αVβ3 increases glioblastoma cells mobility and progression.

Suesskind D et al. Graefes Arch Clin Exp Ophthalmol 2015; Conjunctival amyloidosis - clinical and histopathologic features.

Application : IHC-P

Reactivity : Human

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