*Optimal dilutions/concentrations should be determined by the researcher.
10μl reagent / 100 μl of whole blood or 10⁶ cells
Not tested in other applications.
This antibody crossreacts with Siglec-14, whose first two Ig domains are almost identical to those of CD170.
PBS, 15mM sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Batch dependent (Please refer to the vial label for the specific concentration.)
Fusion protein composed of human CD170 extracellular domain and Fc region of human IgG1
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
CD170 , CD33L2 , OBBP2 , SIGLEC5 , sialic acid binding Ig like lectin 5
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]
GTX00537-08 FACS Image
FACS analysis of human peripheral blood using GTX00537-08 Siglec-5 antibody [1A5] (PE).