APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
Note :
FACS
10μl reagent / 100 μl of whole blood or 10⁶ cells
|
Not tested in other applications.
Product Note
This antibody crossreacts with Siglec-14, whose first two Ig domains are almost identical to those of CD170.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Fusion protein composed of human CD170 extracellular domain and Fc region of human IgG1
Purification
Purified IgG
Conjugation
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CD170 , CD33L2 , OBBP2 , SIGLEC5 , sialic acid binding Ig like lectin 5
Cellular Localization
Membrane
Background
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]
Database
Research Area
DATA IMAGES
|
GTX00537-08 FACS Image
FACS analysis of human peripheral blood using GTX00537-08 Siglec-5 antibody [1A5] (PE).
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REFERENCE
There are currently no references for Siglec-5 antibody [1A5] (PE) (GTX00537-08). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Siglec-5 antibody [1A5] (PE) (GTX00537-08). Be the first to share your experience with this product.