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Siglec-5 antibody [1A5]

Anti-Siglec-5 antibody [1A5] used in Flow cytometry (FACS). GTX00537

Cat No. GTX00537

Host

Mouse

Clonality

Monoclonal

Clone Name

1A5

Isotype

IgG1

Application

ICC/IF, IHC-Fr, FACS, IP, ELISA

Reactivity

Human, Primate
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
IP Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

Specificity/Sensitivity

This antibody reacts with Siglec-14, whose first two Ig domains are almost identical to those of CD170.

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Fusion protein composed of human CD170 extracellular domain and Fc region of human IgG1

Purification

Protein A purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD170 , CD33L2 , OBBP2 , SIGLEC5 , sialic acid binding Ig like lectin 5

Cellular Localization

Membrane

Background

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]

Database

Research Area

DATA IMAGES

Anti-Siglec-5 antibody [1A5] used in Flow cytometry (FACS). GTX00537

GTX00537 FACS Image

FACS analysis of human peripheral blood using GTX00537 Siglec-5 antibody [1A5].

REFERENCE

There are currently no references for Siglec-5 antibody [1A5] (GTX00537). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Siglec-5 antibody [1A5] (GTX00537). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf