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Slc22A17 antibody

Anti-Slc22A17 antibody used in IHC (Paraffin sections) (IHC-P). GTX85032
Anti-Slc22A17 antibody used in IHC (Paraffin sections) (IHC-P). GTX85032
Anti-Slc22A17 antibody used in IHC (Paraffin sections) (IHC-P). GTX85032
Anti-Slc22A17 antibody used in Western Blot (WB). GTX85032

Cat. No. GTX85032

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all SLC22A17 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

Positive Control

SK-N-SH Cell Lysate(GTX23956)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Slc22A17 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human Slc22A17.The immunogen is located within the last 50 amino acids of Slc22A17.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier family 22 member 17 , 24p3R , BOCT , BOIT , NGALR , NGALR2 , NGALR3 , hBOIT

Cellular Localization

Cell membrane

Background

The Slc22 family of organic anion and cation transporters (OATs, OCTs, OCTNs) are transmembrane proteins expressed predominantly in kidney and liver. Each contain 12 predicted alpha-helical transmembrane domains (TMDs) and one large extracellular loop between TMDs 1 and 2. Transporters of the SLC22 family function in different ways such as uniporters that mediate facilitated diffusion in either direction (OCTs), as anion exchangers (OAT1, OAT3 and URAT1), and as Na(+)/l-carnitine cotransporter (OCTN2). Slc22 family members participate in the absorption and/or excretion of drugs, xenobiotics, and endogenous compounds in intestine, liver, and kidney, and perform homeostatic functions in brain and heart. Mutations in the Slc22 family may cause specific diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may change drug absorption or excretion. Recent studies show the expression of Slc22A17 as receptor for Lipocalin 2 is relatively high in hematopoietic stem cells.

Database

Research Area

DATA IMAGES

Anti-Slc22A17 antibody used in IHC (Paraffin sections) (IHC-P). GTX85032

GTX85032 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX85032 Slc22A17 antibody.
Working concentration : 20 μg/ml

Anti-Slc22A17 antibody used in IHC (Paraffin sections) (IHC-P). GTX85032

GTX85032 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX85032 Slc22A17 antibody.
Working concentration : 2.5 μg/ml

Anti-Slc22A17 antibody used in IHC (Paraffin sections) (IHC-P). GTX85032

GTX85032 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX85032 Slc22A17 antibody.
Working concentration : 20 μg/ml

Anti-Slc22A17 antibody used in Western Blot (WB). GTX85032

GTX85032 WB Image

WB analysis of SK-N-SH lysate in (A) the presence and (B) the absence of blocking peptide using GTX85032 Slc22A17 antibody.
Working concentration : 0.5 μg/ml

REFERENCE

Application Reference

Bauvois B et al. Biomedicines 2023; 11 (9) The Value of Neutrophil Gelatinase-Associated Lipocalin Receptor as a Novel Partner of CD38 in Chronic Lymphocytic Leukemia: From an Adverse Prognostic Factor to a Potential Pharmacological Target?
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399