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Slitrk5 antibody

Anti-Slitrk5 antibody used in Western Blot (WB). GTX85414
Anti-Slitrk5 antibody used in IHC (Paraffin sections) (IHC-P). GTX85414
Anti-Slitrk5 antibody used in IHC (Paraffin sections) (IHC-P). GTX85414

Cat. No. GTX85414

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($419)
See all SLITRK5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

107 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , 3T3 Cell Lysate

Product Note

This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Slitrk5 antibody was raised against a 14 amino acid synthetic peptide from near the center of human Slitrk5.The immunogen is located within amino acids 310 - 360 of Slitrk5.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SLIT and NTRK like family member 5 , LRRC11 , bA364G4.2

Cellular Localization

Membrane

Background

SLIT and NTRK-like family 5 (Slitrk5) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk5 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

Database

Research Area

DATA IMAGES

Anti-Slitrk5 antibody used in Western Blot (WB). GTX85414

GTX85414 WB Image

WB analysis of 3T3 cell lysate in the (A) absence or (B) presence of blocking peptide using GTX85414 Slitrk5 antibody.
Working concentration : 1 μg/ml

Anti-Slitrk5 antibody used in IHC (Paraffin sections) (IHC-P). GTX85414

GTX85414 IHC-P Image

IHC-P analysis of human brain tissue using GTX85414 Slitrk5 antibody.
Working concentration : 2.5 μg/ml

Anti-Slitrk5 antibody used in IHC (Paraffin sections) (IHC-P). GTX85414

GTX85414 IHC-P Image

IHC-P analysis of human brain tissue using GTX85414 Slitrk5 antibody.
Working concentration : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419