GeneTex
United States (US)

Sodium Channel-pan antibody

Sodium-Channel-pan-antibody-GTX87930-IHC-1_18122102_334.jpg
Sodium-Channel-pan-antibody-GTX87930-WB-1_18122102_830.jpg

Cat No. GTX87930

Host Rabbit
Clonality Polyclonal
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

We recommend the following starting dilutions:

WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:20000

Optimal dilutions should be determined experimentally by the end user.

Calculated MW

227 kDa. ( Note )

Specificity/Sensitivity

Sodium Channel-pan Antibody detects endogenous levels of total Sodium Channel protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Sodium Channel.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

SCN5A, Sodium channel protein, cardiac muscle alphasubunit, Sodium Channelpan, CIN5, cardiac muscle alpha-subunit, HH1, cardiac muscle alpha subunit

Background

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.

Research Area

DATA IMAGES
Sodium-Channel-pan-antibody-GTX87930-IHC-1_18122102_334.jpg

GTX87930 IHC-P Image

Immunohistochemistry analysis of paraffin-embedded human heart tissue, using Sodium Channel-pan Antibody. The picture on the right is treated with the synthesized peptide.

Sodium-Channel-pan-antibody-GTX87930-WB-1_18122102_830.jpg

GTX87930 WB Image

Western blot analysis of extracts from HuvEc cells, using Sodium Channel-pan Antibody. The lane on the right is treated with the synthesized peptide.

Package List Price ($)
$ 339