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Somatostatin antibody [YC7]

Cat No. GTX39061

Reference 2
Host Rat
Clonality Monoclonal
Clone Name YC7
Isotype IgG2b
Application ICC/IF, IHC-P, IHC-Fr
Reactivity Human, Mouse, Rat, Zebrafish, Guinea pig, Pig
Package
200 μl ($399)
See all Somatostatin products
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

13 kDa. ( Note )

Specificity/Sensitivity

The epitope recognised by this antibody lies within the 1-14 amino acid sequence of cyclic somatostatin.
PROPERTIES

Form

Liquid

Buffer

Tissue Culture Supernatant with 0.05% Thiomersal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Somatostatin conjugated to thyroglobulin.

Purification

Tissue Culture Supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Somatostatin,Smst,Sst

Background

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Application Reference

Zhang W et al. Biochem Biophys Res Commun 2017; (Epub) neuromedin u suppresses glucose-stimulated * secretion in pancreatic β cells.
Application : ICC/IF
Reactivity : Mouse
Masjkur J et al. J Biol Chem 2014; hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and * release.
Application : IHC-Fr
Reactivity : Mouse
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Package List Price ($)
$ 399