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Sorbitol Dehydrogenase antibody, C-term

Anti-Sorbitol Dehydrogenase antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89635
Anti-Sorbitol Dehydrogenase antibody, C-term used in Western Blot (WB). GTX89635

Cat. No. GTX89635

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all Sorbitol Dehydrogenase products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.3μg/ml
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89635-PEP).

Predict Reactivity

Rat, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence KIMLKCDPSDQNP, from the C Terminus of the protein sequence according to NP_003095.2.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sorbitol dehydrogenase , HEL-S-95n , SORD1

Background

Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]

Database

Research Area

DATA IMAGES

Anti-Sorbitol Dehydrogenase antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89635

GTX89635 IHC-P Image

IHC-P analysis of human prostate using GTX89635 Sorbitol Dehydrogenase antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 5μg/ml

Anti-Sorbitol Dehydrogenase antibody, C-term used in Western Blot (WB). GTX89635

GTX89635 WB Image

WB analysis of mouse kidney lysate using GTX89635 Sorbitol Dehydrogenase antibody, C-term.
Dilution : 0.1μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399