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Src (phospho Tyr416) antibody [EPR6239(2)]

Anti-Src (phospho Tyr416) antibody [EPR6239(2)] used in Western Blot (WB). GTX63902

Cat. No. GTX63902

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 EPR6239(2)

Isotype

 IgG

Application

 WB

Reactivity

 Human, Rat
Package
100 μl ($399)
See all Src products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
Not tested in other applications.

Calculated MW

60 kDa. ( Note )

Product Note

Based on sequence homology, this antibody may cross with other Src family members such as YES1 , FYN proteins when phosphorylated at the equivalent sites.

PROPERTIES

Form

Liquid

Buffer

PBS (pH7.2), 50% Glycerol, 0.05% BSA

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A phospho specific peptide corresponding to residues surrounding Tyrosine 418 of human Src was used as an immunogen. The Tyr418 of human Src is equivalent to Tyr416 of chicken Src.

Purification

Tissue culture supernatant

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,488.

TARGET

Synonyms

SRC proto-oncogene, non-receptor tyrosine kinase , ASV , SRC1 , THC6 , c-SRC , p60-Src

Cellular Localization

Cell membrane , Mitochondrion inner membrane , Nucleus , Cytoplasm, cytoskeleton

Background

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Src (phospho Tyr416) antibody [EPR6239(2)] used in Western Blot (WB). GTX63902

GTX63902 WB Image

Western blot analysis on A431 cell lysates using Src (phospho Tyr416) antibody [EPR6239(2)] (GTX63902). Cells were either (A) untreated or (B) treated with Pervanadate.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399