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StAR antibody [MSVA-740R] HistoMAX™

HistoMAX
Anti-StAR antibody [MSVA-740R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04483
Anti-StAR antibody [MSVA-740R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04483
Anti-StAR antibody [MSVA-740R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04483

Cat. No. GTX04483

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 MSVA-740R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($679),
100 μl ($299)
See all StAR products
PRODUCT

Summary

This antibody was validated on 76 different Normal Tissues by IHC-P.

Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Manual staining : Heat-induced antigen retrieval for 5 minutes in an autoclave at 121ºC in pH 7.8 Tris-EDTA-based Target Retrieval Solution buffer.
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

Positive Control

Adrenal gland: A moderate to strong cytoplasmic StAR staining should be seen in the vast majority of adrenocortical cells.

Negative Control

Colon: All cells must not show any StAR staining.

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format)

Preservative

0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human STAR fragment

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

steroidogenic acute regulatory protein , STARD1

Cellular Localization

Mitochondrion

Background

The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-StAR antibody [MSVA-740R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04483

GTX04483 IHC-P Image

IHC-P analysis of human adrenocortical carcinoma tissue section using GTX04483 StAR antibody [MSVA-740R] HistoMAX™.
Adrenocortical carcinoma showing strong StAR immunostaining of tumor cells.

Anti-StAR antibody [MSVA-740R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04483

GTX04483 IHC-P Image

IHC-P analysis of human leydig cells using GTX04483 StAR antibody [MSVA-740R] HistoMAX™.
Strong cytoplasmic StAR immunostaining of Leydig cells.

Anti-StAR antibody [MSVA-740R] HistoMAX™ used in IHC (Paraffin sections) (IHC-P). GTX04483

GTX04483 IHC-P Image

IHC-P analysis of human adrenal cortical tissue section using GTX04483 StAR antibody [MSVA-740R] HistoMAX™.
Strong StAR staining of normal adrenocortical cells.

REFERENCE

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REVIEW

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Package List Price ($)
$ 679
$ 299