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Stathmin 1 (phospho Ser38) antibody

Anti-Stathmin 1 (phospho Ser38) antibody used in Western Blot (WB). GTX50261
Anti-Stathmin 1 (phospho Ser38) antibody used in IHC (Paraffin sections) (IHC-P). GTX50261

Cat. No. GTX50261

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all Stathmin 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

17 kDa. ( Note )

Predict Reactivity

Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around phosphorylation site of serine 38 (P-L-S(p)-P-P) derived from human Stathmin 1.

Purification

Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Conjugation

Unconjugated

RRID

AB_11167586

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

stathmin 1 , C1orf215 , LAP18 , Lag , OP18 , PP17 , PP19 , PR22 , SMN

Cellular Localization

Cytoplasm, cytoskeleton

Background

This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

Database

Research Area

DATA IMAGES

Anti-Stathmin 1 (phospho Ser38) antibody used in Western Blot (WB). GTX50261

GTX50261 WB Image

WB analysis of extracts from K562 cells untreated or treated with starvation using GTX50261 Stathmin 1 (phospho Ser38) antibody.

Anti-Stathmin 1 (phospho Ser38) antibody used in IHC (Paraffin sections) (IHC-P). GTX50261

GTX50261 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX50261 Stathmin 1 (phospho Ser38) antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide

REFERENCE

Application Reference

YY Hsieh et al. Mol Oncol 2023; Repositioning VU-0365114 as a novel microtubule-destabilizing agent for treating cancer and overcoming drug resistance
Xu K et al. J Biol Chem 2015; 290 (31) : 19245-60 Down-regulation of Stathmin Is Required for the Phenotypic Changes and Classical Activation of Macrophages.
Application : WB
Reactivity : Mouse
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399