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Substance P antibody [NC1/34]

Cat No. GTX38990

Reference 1

Host

 Rat

Clonality

 Monoclonal

Clone Name

 NC1/34

Isotype

 IgG2a

Application

 ICC/IF, IHC-P, IHC-Fr

Reactivity

 Human, Mouse, Rat, Zebrafish, Rabbit, Sheep, Bovine, Chicken, Guinea pig, Pig, Bichir, Bullfrog, Calanus sp., Camel, Chinchilla, Cockroach, Cowbird, Crayfish, Homarus sp., Lamprey, Mudpuppy, Panilurus sp., pigeon, Spadefoot toad
Package
100 μl ($429)
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APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
IHC-P 1/100-1/200
IHC-Fr 1/100-1/200
Not tested in other applications.

Calculated MW

15 kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes the COOH terminal end of substance P.

Predict Reactivity

Amphibians(>80% identity)

PROPERTIES

Form

Liquid

Buffer

Tissue Culture Supernatant with 0.05% Thiomersal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Immunogen

Substance P conjugated to Bovine Serum Albumin.

Purification

Tissue Culture Supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Tachykinin Precursor 1 , Hs.2563 , Nk2 , Nkna , Npk , Tac2 , Tac1

Background

This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Application Reference

Tan WQ et al. Br J Pharmacol 2018; (Epub) Angiotensin-converting enzyme inhibitor works as a scar formation inhibitor by downregulating Smad and TAK1 pathways in mice.
Application : IHC-P
Reactivity : Mouse
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REVIEW

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Package List Price ($)
$ 429