GeneTex
United States (US)

Suppressor of Fused antibody

GTX33530_20180530_IHC-P_18121410_405.jpg
GTX33530_20180530_WB_18121410_265.jpg

Cat No. GTX33530

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

54 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 325-484 of human SUFU (NP_057253.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Sufu Negative Regulator Of Hedgehog Signaling,Jbts32,Pro1280,Sufuh,Sufuxl,Sufu

Background

The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES
GTX33530_20180530_IHC-P_18121410_405.jpg

GTX33530 IHC-P Image

IHC-P analysis of human stomach tissue using GTX33530 Suppressor of Fused antibody.
Dilution : 1:100

GTX33530_20180530_WB_18121410_265.jpg

GTX33530 WB Image

WB analysis of various samples using GTX33530 Suppressor of Fused antibody.
Dilution : 1:1000
Loading : 25μg per lane