GeneTex
United States (US)

Surfactant protein D antibody [SPDE]

Cat No. GTX30746

Host Mouse
Clonality Monoclonal
Clone Name SPDE
Isotype IgG2b
Application WB, IHC-Fr
Reactivity Human, Rat
APPLICATION

Application Note

For IHC-Fr: Use at a dilution of 1:250. For WB: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user

Specificity/Sensitivity

Rat: SPDE recognizes a conformational epitope of SP-D Other Species: Positive on human tissues.
PROPERTIES

Form

Liquid

Buffer

Preservative: 0.1% Sodium Azide; Constituents: PBS. pH 7.2

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Purified rat surfactant protein D from bronchoalveolar lavage.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Cellular Localization

Secreted

Background

Surfactant protein D is a calcium ion dependent carbohydrate binding protein and is structurally similar to other C type mammalian lectins, such as conglutinin and SPA. It has a molecular size of approximately 43kDa in its reduced state, 620kDa in non dissociating conditions. Surfactant protein D enhances the production of oxygen radicals by rat alveolar macrophages and regulates some actions of SPA, which is the most abundant surfactant protein. Surfactant protein D is synthesized and secreted by alveolar epithelial type II cells.

Research Area

Package List Price ($)
$ 319