GeneTex
United States (US)

Survivin (phospho Thr34) antibody

GTX30488_1413_WB_18121410_387.jpg
GTX30488_214_ICC-IF_18121410_302.jpg

Cat No. GTX30488

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse, Bovine, Cat, Dog, Pig, Primate
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

16 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Tris-Citrate/Phosphate pH 7.0 - 8.0, 0.1% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1mg/ml

Antigen Species

Human

Immunogen

A synthetic peptide with a phosphorylated Threonine (amino acid 34) corresponding to human Survivin. [UniProt# O15392]

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

API4 antibody , EPR-1 antibody

Cellular Localization

Cytoplasm,Nucleus,Centromere

Background

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX30488_1413_WB_18121410_387.jpg

GTX30488 WB Image

WB analysis of phosphorylated Survivin protein (lane 1) and Non-phosphorylated Survivin protein (lane 2) using GTX30488 Survivin (phospho Thr34) antibody.

GTX30488_214_ICC-IF_18121410_302.jpg

GTX30488 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX30488 Survivin (phospho Thr34) antibody.
Green : primary antibody
Blue : DAPI

Package List Price ($)
$ 379