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Syk antibody [SPM147]

Anti-Syk antibody [SPM147] used in Immunohistochemistry (IHC). GTX15238

Cat. No. GTX15238

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 SPM147

Isotype

 IgG2a

Application

 WB, IHC-P, IP, IHC

Reactivity

 Human
Package
500 μl ($399)
See all Syk products

APPLICATION

Application Note

For IHC-P: Use at a dilution of 1-100 for 10 min. at RT. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. For IP: Use at a concentration of 2ug antibody/mg protein lysate. For WB: Use at a concentration of 1 μg/ml. Predicted molecular weight: 72 kDa. Optimal dilutions/concentrations should be determined by the researcher

Calculated MW

72 kDa. ( Note )

Positive Control

Raji, K562, HL-60, U937 cells or lymphoma.

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide - amino acids 313-339 of Human Syk.

Purification

Protein G affinity purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

spleen associated tyrosine kinase , p72-Syk

Cellular Localization

Cell membrane , Cytoplasm, cytosol

Background

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Database

Research Area

DATA IMAGES

Anti-Syk antibody [SPM147] used in Immunohistochemistry (IHC). GTX15238

GTX15238 IHC Image

Human lymphoma stained with GTX15238 1/100 dilution

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399