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Synaptophysin antibody

Cat No. GTX72796

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC

Reactivity

Human
Package
7 ml ($219)

APPLICATION

Application Note

Immunohistochemistry (IHC) for formalin-fixed paraffin embedded (FFPE) tissue sections and frozen sections. Dilute 1:100-1:200 using polymer or streptavidin ~biotin system for 30 mins at room temperature. The Prediluted antibody is ready to be used. This antibody requires antigen retriever (boiling FFPE tissue sections in 10 mM citrate buffer, pH 6.0 for 10-20 mins. followed by cooling at room temp. for 20 mins).

Calculated MW

34 kDa. ( Note )

Positive Control

Human pancreas or GI tumor

Specificity/Sensitivity

This antibody reacts with Synaptophysin in neuroendocrine neoplasm of neural as well as epithelial type.

PROPERTIES

Form

Liquid

Buffer

10 mM PO4, 150 mM NaCl, pH 7.4, containing 1% BSA and 0.05% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

10 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide from C-terminus of human Synaptophysin.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Synaptophysin , Mrx96 , Mrxsyp , Syp

Cellular Localization

Cytoplasmic

Background

This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011]

Database

Research Area

REFERENCE

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 219