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Synaptotagmin 1 (phospho Ser312) + Synaptotagmin 2 (phospho Ser309) antibody

Anti-Synaptotagmin 1 (phospho Ser312) + Synaptotagmin 2 (phospho Ser309) antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50249

Cat. No. GTX50249

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF

Reactivity

 Human
Package
100 μl ($399)
See all Synaptotagmin 1 + Synaptotagmin 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1:100-1:200
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

Product Note

The sequence around Synaptotagmin 1 (phospho Ser312) is conserved with the sequence around Synaptotagmin 2 (phospho Ser309).

Predict Reactivity

Mouse, Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around phosphorylation site of serine 309 (G-L-S(p)-D-P) derived from human Synaptotagmin.

Purification

Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

synaptotagmin 1 , BAGOS , P65 , SVP65 , SYT

Cellular Localization

Cytoplasm

Background

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).[supplied by OMIM, Jul 2010]

Database

Research Area

DATA IMAGES

Anti-Synaptotagmin 1 (phospho Ser312) + Synaptotagmin 2 (phospho Ser309) antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50249

GTX50249 ICC/IF Image

ICC/IF analysis of methanol-fixed HeLa cells using GTX50249 Synaptotagmin 1 (phospho Ser312) + Synaptotagmin 2 (phospho Ser309) antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399