Form
Liquid
Buffer
PBS pH7.2
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Concentration
400 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Chickens were immunized with four synthetic peptide / keyhole limpet hemocyanin (KLH) conjugates.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
SYT , p65 , Synaptotagmin1 , DKFZp781D2042 , Synaptotagmin I , SVP65 , SytI , Synaptotagmin-1 , Synaptotagmin 1
Cellular Localization
Cytoplasmic
Background
Human Synaptotagmin-1 is a 47,442 dalton protein (422 amino acids) associated with pre-synaptic terminals of the PNS and CNS. Synaptotagmin-1 binds calcium in synaptic terminals and initiates the fusion of vesicles with the pre-synaptic membrane. This protein is also believed to be the target of proteolytic activity associated with Botulinum neurotoxin A.
Research Area