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Syndecan-1 / CD138 antibody [SDC1/4378R]

Anti-Syndecan-1 / CD138 antibody [SDC1/4378R] used in IHC (Paraffin sections) (IHC-P). GTX02707
Anti-Syndecan-1 / CD138 antibody [SDC1/4378R] used in IHC (Paraffin sections) (IHC-P). GTX02707

Cat. No. GTX02707

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 SDC1/4378R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all Syndecan-1 / CD138 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2 μg/ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to human CD138 residues within aa 200-300

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

syndecan 1 , CD138 , SDC , SYND1 , syndecan

Cellular Localization

Membrane , Secreted

Background

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Syndecan-1 / CD138 antibody [SDC1/4378R] used in IHC (Paraffin sections) (IHC-P). GTX02707

GTX02707 IHC-P Image

IHC-P analysis of human small intestine tissue section using GTX02707 Syndecan-1 / CD138 antibody [SDC1/4378R].

Anti-Syndecan-1 / CD138 antibody [SDC1/4378R] used in IHC (Paraffin sections) (IHC-P). GTX02707

GTX02707 IHC-P Image

IHC-P analysis of human small intestine tissue section using GTX02707 Syndecan-1 / CD138 antibody [SDC1/4378R].

REFERENCE

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REVIEW

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Package List Price ($)
$ 529