For IP: Use at a concentration of 10 μg/ml. For WB: Use at a concentration of 1 μg/ml. Optimal dilutions/concentrations should be determined by the researcher.
HeLa Cell Lysate, Rat Brain Tissue Extract, Mouse Brain Tissue Extract
Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide and 50% glycerol
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic peptide: MRDRLPDLTACRKSDDGDN conjugated to KLH, corresponding to amino acids 1-19 of Rat Syntaxin 2.
Immunogen affinity purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Syntaxin 2 , Epim , Stx2
Syntaxin 2, also known as epimorphin, is a 35 kDa type II integral membrane that belongs to the t SNARE family, a group of proteins involved in protein transport. Syntaxin 2 was first identified as a factor that promotes branching morphogenesis in mammary epithelial cells. Studies using pancreatic exocrine acinar cells, in which the exocytic pathways are well defined, show primary localization of syntaxin 2 to the apical plasma membrane. Homologs of syntaxin 2 have been identified in various eukaryotes ranging from yeast to human. Neuronal syntaxin is a component of a 20S complex implicated in vesicle docking and fusion, which involves its interaction with syntaxin through a ATP dependent reaction modulated by synaptotagmin, SNAP 25, alpha SNAP, and NSF.