GeneTex
United States (US)

Syntaxin 2 antibody

Syntaxin-2-antibody_IHC_GTX12369-1_18121411_478.jpg
Syntaxin-2-antibody_WB_GTX12369-1_18121411_769.jpg

Cat No. GTX12369

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IP, IHC
Reactivity Human, Mouse, Rat, Rabbit, Sheep, Drosophila, Hamster, Pig, Monkey
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IP Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

33 kDa kDa. ( Note )

Positive Control

HeLa Cell Lysate, Rat Brain Tissue Extract, Mouse Brain Tissue Extract
PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide and 50% glycerol

Concentration

1mg/ml

Antigen Species

Rat

Immunogen

Synthetic peptide: MRDRLPDLTACRKSDDGDN conjugated to KLH, corresponding to amino acids 1-19 of Rat Syntaxin 2.

Purification

Immunogen affinity purified

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Syntaxin 2, 25130, Syntaxin2, Epim

Background

Syntaxin 2, also known as epimorphin, is a 35 kDa type II integral membrane that belongs to the t SNARE family, a group of proteins involved in protein transport. Syntaxin 2 was first identified as a factor that promotes branching morphogenesis in mammary epithelial cells. Studies using pancreatic exocrine acinar cells, in which the exocytic pathways are well defined, show primary localization of syntaxin 2 to the apical plasma membrane. Homologs of syntaxin 2 have been identified in various eukaryotes ranging from yeast to human. Neuronal syntaxin is a component of a 20S complex implicated in vesicle docking and fusion, which involves its interaction with syntaxin through a ATP dependent reaction modulated by synaptotagmin, SNAP 25, alpha SNAP, and NSF.
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Database

Research Area

DATA IMAGES
Syntaxin-2-antibody_IHC_GTX12369-1_18121411_478.jpg

GTX12369 IHC Image

Immunohistochemistry analysis of human brain, cerebellum tissue stained with Syntaxin 2, pAb at 10µg/ml.

Syntaxin-2-antibody_WB_GTX12369-1_18121411_769.jpg

GTX12369 WB Image

Western blot analysis of human Jurkat cell lysate, probed with Syntaxin 2 pAb