*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
HeLa Cell Lysate, Rat Brain Tissue Extract, Mouse Brain Tissue Extract
Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide and 50% glycerol
Synthetic peptide: MRDRLPDLTACRKSDDGDN conjugated to KLH, corresponding to amino acids 1-19 of Rat Syntaxin 2.
Immunogen affinity purified
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Syntaxin 2, 25130, Syntaxin2, Epim
Syntaxin 2, also known as epimorphin, is a 35 kDa type II integral membrane that belongs to the t SNARE family, a group of proteins involved in protein transport. Syntaxin 2 was first identified as a factor that promotes branching morphogenesis in mammary epithelial cells. Studies using pancreatic exocrine acinar cells, in which the exocytic pathways are well defined, show primary localization of syntaxin 2 to the apical plasma membrane. Homologs of syntaxin 2 have been identified in various eukaryotes ranging from yeast to human. Neuronal syntaxin is a component of a 20S complex implicated in vesicle docking and fusion, which involves its interaction with syntaxin through a ATP dependent reaction modulated by synaptotagmin, SNAP 25, alpha SNAP, and NSF.
GTX12369 IHC Image
Immunohistochemistry analysis of human brain, cerebellum tissue stained with Syntaxin 2, pAb at 10µg/ml.
GTX12369 WB Image
Western blot analysis of human Jurkat cell lysate, probed with Syntaxin 2 pAb